Hideo Kojima har flere gange tidligere varslet at han var færdig med Metal Gear Solid-serien, for et par måneder senere at annoncere at han arbejder på et nyt spil i serien. Det uddyber han nu alt sammen lidt i et nyt interview med Game Informer, hvor det blandet andet lyder:
"Ideally I would like to step out from the Metal Gear franchise as a producer and dedicate myself to other games. So far that has proven to be a bit difficult. Alien is a very successful example [of a new director coming in]. Unfortunately in our case it's more like Terminator, that once Cameron steps out of it there was kind of a mess."
"I've been working in the Metal Gear franchise for over 25 years. This world has allowed me to tell a lot of the things that I wanted to say. That said, it has a very specific worldview and a very specific set of game elements. I'll probably be saying this until I die, but there are still more things I want to tell, more things I want to communicate, and more things I want to experiment with."