I en nylig post på Binding of Isaacs hjemmeside, blev der hintet til et nyt projekt af skaberen Edmund McMillen i samarbejde med Closure-programmør Tyler Glaiel.
"On a side note not many of you know this but Tyler and I have been in crunch mode for the past 3 months trying to finish this secret project," skriver McMillen. "We are coming close to announcing it and its release date, so keep and eye out for it, I don't want to spoil the fun yet but I can say this:
"It's hard, it's weird, it's personal, it has amazing controls, it's a totally new unannounced IP and its easily one of the largest games I've ever made level wise."
Som PC Gamer meget korrekt bemærker, kunne dette både være en helt ny IP eller det som Glaiel teasede på YouTube forrige år.